Pregnancy Blood Tests Could Reveal Future Heart Risks for Women

Cardiovascular disease remains the top cause of death for women globally. Around 40% will die from conditions like heart attacks, strokes, or heart failure in their lifetime. Now, new research suggests that risks can be spotted far earlier—even during pregnancy.

A study by Freiburg University Hospital tracked over 2,000 pregnant women for an average of 12 years. Researchers found that high levels of the blood marker sFlt-1 in the final trimester, combined with pregnancy-related high blood pressure, signalled a greater chance of severe heart problems later in life. Affected women often developed conditions by their early 40s.

The team also discovered that pairing the blood marker with the mother's age gave a clearer risk prediction than traditional factors like blood pressure or cholesterol alone. Common risk factors—such as obesity, smoking, diabetes, and lack of exercise—still play a major role in heart disease.

In response, Freiburg University Hospital has launched a dedicated follow-up clinic. The service targets women who had high blood pressure during pregnancy, offering early screening to improve long-term heart health.

The findings highlight a potential way to identify at-risk women years before symptoms appear. Early detection through pregnancy-related markers could lead to better prevention and treatment. The clinic's work aims to reduce the heavy toll of cardiovascular disease on women's lives.