New Italian Study Reveals Hidden Risks in Women's Heart Attacks

A new Italian study is examining acute coronary syndromes (ACS) in women to better understand their unique risks. The GEDI-ACS registry is tracking 100 female patients across multiple cardiovascular centres. Early findings from the first 68 participants reveal key patterns in health, symptoms, and complications.

The registry focuses on women with ACS, a condition linked to ischaemic heart disease—the world's leading cause of death. Among the first 68 enrolled, the average age is 68, with 7.4% identifying as non-Caucasian. Most had no prior heart issues, as ACS marked the first cardiovascular event for 86% of them.

Chest pain was the most common symptom, reported by 88.2% of the women. The data also show high rates of cardiovascular risk factors: 83.6% had dyslipidaemia, 77.9% suffered from hypertension, and half had a history of smoking.

Beyond heart health, pregnancy-related complications were notable. Nearly a third (32.3%) had experienced miscarriage, while 16.2% went through premature menopause. Another concern was health literacy, with 85.3% showing low levels, potentially hindering self-care and treatment adherence.

The study collects a wide range of data, including sex-specific, socioeconomic, and molecular factors. Its goal is to develop tailored strategies for diagnosing and managing ACS in women, who face higher mortality risks than men.

The GEDI-ACS registry highlights critical gaps in women's heart health, from high-risk factors to low health literacy. By analysing these findings, researchers aim to improve diagnosis and treatment for female ACS patients. The study continues to enrol participants, with full results expected in the coming years.